About Yinzhi Lang
Yinzhi Lang, PhD, is a Research Assistant Professor in the Department of Pharmacotherapy and Translational Research at the UF College of Pharmacy. Dr. Lang’s research focus on developing novel assays and elucidating the mechanism of drug action and resistance via LC-MS and QSP modeling approach.
Dr. Lang completed her PhD program in 2016 from Ocean University of China. For her doctoral research, she developed advanced biochemical and bioanalytical methods for extracting and analyzing complex biological macromolecules (glycans, proteoglycans, glycoproteins and glycolipids) from various tissues of plants, animals and humans. Between 2016 and 2018, Dr. Lang worked as a senior Scientist in Shanghai Greenvalley Pharmaceutical Co.Ltd. She played an integrated role on developing instrumental analysis methods (LC-MS, CE-MS & GC-MS) for QC and ADME study of an innovative anti-Alzheimer agent GV-971 (Phase III, NCT04520412).
In 2018, Dr. Lang joined the College of Pharmacy at UF as a Postdoc and has received systematic training in antimicrobial pharmacology, pharmacokinetics and pharmacodynamics from Dr. Bulitta and his collaborators. She has created a series of UPLC-MRM-MS/MS assays to quantify the target site penetration of antibacterial in Gram-negative bacteria, and accumulation of antiviral drugs in mammalian cells. Moreover, she employed LC-MS/MS based proteomics, metabolomics and lipidomics to characterize microbial biomolecules. In 2021, Dr. Lang was appointed as a Research Assistant Professor in the college. She is now significantly contributing to the development of Quantitative and Systems Pharmacology (QSP) models with Dr. Bulitta, which can integrate these mechanistic data with pathogen killing, resistance, tolerance and persistence to rationally optimize anti-infective therapy. Dr. Lang is leading several funded anti-infection projects to create novel insights to combat serious infections.
National Computer Rank Examination (NCRE) (China)Visual C++ (Rank II) Certificate
National Computer Rank Examination (NCRE) (China)Internet technology (Rank III) Certificate
- Infectious diseases
- Quantitative and Systems Pharmacology modeling
- Translational and clinical pharmacology
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