Khoa Nguyen

Khoa Nguyen, Pharm.D.

Clinical Assistant Professor

Department: Pharmacotherapy & Translational Research
Business Phone: (352) 273-9418
Business Email: nguyen.khoa@ufl.edu

About Khoa Nguyen

Khoa Nguyen, Pharm.D., received his Doctor of Pharmacy degree from the University of Michigan, College of Pharmacy. He then completed a fellowship in medical informatics at the VA Indianapolis, HSR&D. After his fellowship, he joined the Regenstrief Institute, Center for Health Services Research as a research scientist and Purdue University, College of Pharmacy as a Visiting Assistant Professor. Currently, Dr. Nguyen is a Clinical Assistant Professor in the Department of Pharmacotherapy and Translational Research at the University of Florida, College of Pharmacy. His clinical practice is within the UF Health Personalized Medicine Program to help develop and improve pharmacogenomic clinical decision support. Additionally, he serves as a faculty liaison at the UF CTSI Integrated Data Repository (IDR) Services to support both research data requests and research IT integration into UF Health electronic health record (EHR) system.

Dr. Khoa Nguyen’s research interests include medical informatics, human-computer interaction, pharmacogenomics, and artificial intelligence (AI). His research focused on improving patient safety through human factor engineering and health information technology. Specifically, Dr. Nguyen wants to utilize human factor engineering, and human-computer interaction method to enhance the implementation of pharmacogenomic clinical decision supports (PGx-CDS). PGx-CDS, when implemented, can foster pharmacogenomics service to predict and prevent severe adverse drug reactions from genetic mutations. Finally, Dr. Nguyen wants to improve the integration of AI tools into EHR systems to assist clinical decision-making. Current projects include the integration of a machine-learning opioid prediction and risk stratification into the UF EHR system as well as develop an AI prediction model and CDS to improve PGx uptake.

Accomplishments

Best Poster by a Postdoctoral Fellow
2018 · American Association of College of Pharmacy
Local Initiated Project Award
2016-2018 · Health Services Research & Development, VA Indianapolis
Zaccardelli Family Pharmacy Scholarship
2013-2015 · University of Michigan, College of Pharmacy

Teaching Profile

Courses Taught
2020-2021
PHA7939 Journal Club in Pharmaceutical Sciences
2019
PHA5878C Pt Care 3: Cv and Pulm
2021-2023
PHA7900 Journal Club in Pharmaceutical Research
2022
PHA5933 Select Top Pharmacy
2023-2024
PHA5243 Principles of Pharmacy Informatics
2023-2024
PHA6935 Selected Topics in Pharmacy
2024
PHA6247 Principles of Pharmacy Informatics

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-0096-0293

Publications

2023
Clinician Response to Pharmacogenetic Clinical Decision Support Alerts.
Clinical pharmacology and therapeutics. 114(6):1350-1357 [DOI] 10.1002/cpt.3051. [PMID] 37716912.
2023
Implementation of CYP2C19 genotyping to guide proton pump inhibitor use at an academic health center.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 80(15):994-1003 [DOI] 10.1093/ajhp/zxad099. [PMID] 37166240.
2023
Lessons from clinical implementation of a preemptive pharmacogenetic panel as part of a testing pilot program with an employer-sponsored medical plan.
Frontiers in genetics. 14 [DOI] 10.3389/fgene.2023.1249003. [PMID] 37680199.
2022
Assessment of a Manual Method versus an Automated, Probability-Based Algorithm to Identify Patients at High Risk for Pharmacogenomic Adverse Drug Outcomes in a University-Based Health Insurance Program.
Journal of personalized medicine. 12(2) [DOI] 10.3390/jpm12020161. [PMID] 35207649.
2022
Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation
. 203-221
2022
Clinical non-effectiveness of clopidogrel use for peripheral artery disease in patients with CYP2C19 polymorphisms: a systematic review.
European journal of clinical pharmacology. 78(8):1217-1225 [DOI] 10.1007/s00228-022-03346-7. [PMID] 35657416.
2022
Dosing profiles of concurrent opioid and benzodiazepine use associated with overdose risk among US Medicare beneficiaries: group‐based multi‐trajectory models
Addiction. 117(7):1982-1997 [DOI] 10.1111/add.15857.
2022
How to Implement a Pharmacogenetics Service at your Institution.
Journal of the American College of Clinical Pharmacy : JACCP. 5(11):1161-1175 [DOI] 10.1002/jac5.1699. [PMID] 36589694.
2022
Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.
Clinical and translational science. 15(10):2479-2492 [DOI] 10.1111/cts.13376. [PMID] 35899435.
2022
Strategies prescribers and pharmacists use to identify and mitigate adverse drug reactions in inpatient and outpatient care: a cognitive task analysis at a US Veterans Affairs Medical Center
BMJ Open. 12(2) [DOI] 10.1136/bmjopen-2021-052401. [PMID] 35190423.
2022
Study protocol for a type III hybrid effectiveness-implementation trial to evaluate scaling interoperable clinical decision support for patient-centered chronic pain management in primary care.
Implementation science : IS. 17(1) [DOI] 10.1186/s13012-022-01217-4. [PMID] 35841043.
2021
Multi-Institutional Implementation of Clinical Decision Support for APOL1, NAT2, and YEATS4 Genotyping in Antihypertensive Management.
Journal of personalized medicine. 11(6) [DOI] 10.3390/jpm11060480. [PMID] 34071920.
2021
Risk Factors for Bleeding and Clinical Ineffectiveness Associated With Clopidogrel Therapy: A Comprehensive Meta-Analysis.
Clinical and translational science. 14(2):645-655 [DOI] 10.1111/cts.12926. [PMID] 33202084.
2021
Utilizing a Human-Computer Interaction Approach to Evaluate the Design of Current Pharmacogenomics Clinical Decision Support.
Journal of personalized medicine. 11(11) [DOI] 10.3390/jpm11111227. [PMID] 34834578.
2020
Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity.
Journal of the American Medical Informatics Association : JAMIA. 27(11):1808-1812 [DOI] 10.1093/jamia/ocaa159. [PMID] 32885823.
2019
Utilizing a user-centered approach to develop and assess pharmacogenomic clinical decision support for thiopurine methyltransferase.
BMC medical informatics and decision making. 19(1) [DOI] 10.1186/s12911-019-0919-4. [PMID] 31623616.
2018
A comprehensive review and meta-analysis of risk factors for statin-induced myopathy.
European journal of clinical pharmacology. 74(9):1099-1109 [DOI] 10.1007/s00228-018-2482-9. [PMID] 29785580.
2018
Usability evaluation of a medication reconciliation tool: Embedding safety probes to assess users’ detection of medication discrepancies.
Journal of biomedical informatics. 82:178-186 [DOI] 10.1016/j.jbi.2018.05.002. [PMID] 29751104.
2017
Medication Use among Veterans across Health Care Systems.
Applied clinical informatics. 8(1):235-249 [DOI] 10.4338/ACI-2016-10-RA-0184. [PMID] 28271121.

Grants

Sep 2023 ACTIVE
Assessing performance of a Hepatitis C Emergency Department (HepC-END) Screening Tool
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2021 ACTIVE
Scaling Interoperable Clinical Decision Support for Patient-Centered Chronic Pain Care
Role: Project Manager
Funding: AGENCY FOR HEALTHCARE RES AND QUALITY
Jul 2021 ACTIVE
Developing and Evaluating a Machine-Learning Opioid Prediction & Risk-Stratification E-Platform (DEMONSTRATE)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Jul 2021 ACTIVE
Using Artificial Intelligence to Identify Patients Most Likely to Benefit from Preemptive Pharmacogenetic Testing
Role: Co-Investigator
Funding: UF HEALTH SHANDS HOSPITAL
Jul 2021 – Dec 2022
Predicting Risky Opioid Therapy e-Care Tool (PROTeCT): Prototype Development and Pilot Testing
Role: Co-Investigator
Funding: UF HEALTH SHANDS HOSPITAL
Nov 2019 – Mar 2022
IPA for Dr. Khoa Nguyen
Role: Principal Investigator
Funding: US DEPT OF VET AFF ROUDEBUSH MED CTR
May 2019 – Jan 2022
Developing a Real-Time Trajectory Tool to Identify Potentially Unsafe Concurrent Opioid and Benzodiazepine Use among Older Adults
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA

Contact Details

Phones:
Business:
(352) 273-9418
Emails:
Addresses:
Business Mailing:
PO Box 100486
GAINESVILLE FL 32610